The main purpose of the PCMA is the detection and evaluation of medical conditions that might create a health risk for the football player during training and competition. Conflicting recommendations exist for the content of the PCMA but a thorough history (cardiovascular and musculoskeletal) and a targeted physical examination are uniformly included. The resting ECG should be added and assessed by a physician with a sufficient background in the medical evaluation of athletes. Currently published Seattle criteria serve well to reduce the number of false positive findings. An echocardiogram is useful for detecting or ruling out structural heart disease (like hypertrophic cardiomyopathy). Further follow-up examinations may include a cardiac MRI and Holter monitoring. Also, laboratory examinations of venous blood can help in detecting relevant diseases of the renal glands and/or diabetes.